Paula's Choice Clinical 1% Retinol Treatment
Updated Nov 8, 2026 ยท Top Retinol creams
8.8/10
Our score
Best for People who already use retinol, want the percent printed on the bottle, and can accept peeling.
Paula's Choice Clinical is a leave-on treatment that prints 1 percent retinol, in a 1 ounce bottle. Michelle Wong used it and peeled for days. She still describes that strength as a high over-the-counter retinol. Use it at night, twice a week at first, over a moisturizer. Leave acids for other nights. People who are new to retinoids should start lower on this list.
What customers like
- Gradually peels off leathery top skin revealing younger softer skin.
- Effective when used correctly on a properly cleaned face.
- Suitable for sensitive skin if introduced gradually.
- Noticeable difference in skin appearance with consistent use.
- Made with quality ingredients ensuring peace of mind.
What customers dislike
- Ineffective if not used on a thoroughly cleaned face.
- Can cause a little bit of stinging especially for sensitive skin.
- Small product size often perceived as a sample.
- Relatively expensive compared to other brands.
- Short product lifespan; runs out quickly.
- Dose
- 1 percent retinol, printed
- Size
- 1 oz
- Use
- Night, twice a week at first
- Expect
- Peeling
Sources: Michelle Wong used this 1 percent treatment and peeled for days
